منابع مشابه
A randomized controlled trial of intravenous montelukast in acute asthma.
Many patients with acute asthma do not respond adequately to currently accepted therapy, including oxygen, beta-agonists, and corticosteroids. Leukotriene receptor antagonists such as montelukast have demonstrated efficacy in chronic asthma, but their efficacy in acute asthma is unknown. In this randomized, double-blind, parallel-group pilot study, adults with moderate to severe acute asthma re...
متن کاملA randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma.
BACKGROUND Current treatments for acute asthma provide inadequate benefit for some patients. Intravenous montelukast may complement existent therapies. OBJECTIVE To evaluate efficacy of intravenous montelukast as adjunctive therapy for acute asthma. METHODS A total of 583 adults with acute asthma were treated with standard care during a < or = 60-minute screening period. Patients with FEV(1...
متن کاملLeukotriene Antagonist Therapy a Randomized, Controlled Trial of Intravenous Montelukast in Acute Asthma
among asthmatic patients. Study Population. Thirty nonsmoking patients with mild/moderate asthma and baseline forced expiratory volume in 1 second values of 70% of predicted values. All patients had experienced no asthma attacks in the previous 2 months and controlled their symptoms with inhaled salbutamol only. Patients did not receive corticosteroids in the 6 months before the study and had n...
متن کاملMontelukast--place in therapy.
H ly , the s tructural and functional differences within the respiratory tract have served as the basis for separating the airway into upper and lower components. As such, asthma and allergic rhinitis have been diagnosed and managed by clinicians as distinct upper and lower airway diseases, respectively. Consistent with this idea of distinct diseases, researchers have developed drugs in years p...
متن کاملMontelukast and Churg-Strauss syndrome
I read with interest the case report by Tuggey and Hosker where Churg-Strauss syndrome was associated with the use of montelukast in an asthmatic patient in whom there was no recent exposure to oral corticosteroid. However, it is worth noting that the patient was using a high dose of inhaled fluticasone propionate (1.5 mg/day) via a large volume spacer prior to the introduction of montelukast. ...
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ژورنال
عنوان ژورنال: Thorax
سال: 2000
ISSN: 0040-6376
DOI: 10.1136/thorax.55.12.1070a